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Gramocef O 200 (Cefixime)

  • Each dispersibletablet contains Cefixime 200mg.
  • Indicated as an antibiotic in the treatment of UTI, RTI and Typhoid fever.
  • Cefixime is a semi-synthetic, oral third-generation cephalosporin, which has marked in vitro bactericidal activity against a wide variety of gram-positive and gram-negative organisms. Bactericidal action of cefixime results from inhibition of bacterial cell-wall synthesis.
  • Children weighing >45 kg or over 12 years of age and adults: One tablet, every 12 hours.
  • Cefixime is contraindicated in patients with a known allergy to cefixime or other cephalosporins or any of the other components of the product.
  • Cefixime should be given with caution to patients who have shown hypersensitivity to other drugs. Prolonged use of cefixime may result in the overgrowth of non-susceptible organisms. Discontinue cefexime in patients who develop, Clostridium difficile Associated Diarrhea. (CDAD).Cefixime may be associated with a fall in prothrombin activity
  • Pregnancy Category B-this drug should be used during pregnancy only if clearly needed.Avoid use during lactation. Gramocef O tablets 200 mg are not recommended for use in children under 10 years of age.
  • Elevated carbamazepine levels have been reported, whencefixime is administered concomitantly. Drug monitoring may be of assistance in detecting alterations in carbamazepine plasma concentrations.Increased prothrombin time, with or without clinical bleeding, has been reported when cefixime is administered concomitantly with warfarin and anticoagulant
  • Most common adverse reactions are gastrointestinal such as diarrhea, nausea, abdominal pain, dyspepsia, and vomiting.
  • Anti-Bacterials