Erox CV 228.5 Dry Syrup (Amoxycillin)

• Composition :
  Each 5 ml contains- Amoxicillin Trihydrate IP equivalent to Amoxicillin 200 mg and Potassium clavulanate IP (as potassium clavulanate diluted IP) equivalent to clavulanic acid 28.5 mg.
• Indications :
  The treatment of infections due to susceptible strains of the designated micro-organisms in the condition of E.N.T infection, skin & skin structure infection, lower respiratory tract infection, genitourinary tract infection, gonorrhea
• Pharmacodynamics :
  Amoxicillin is semisynthetic penicillin (beta-lactam antibiotic) that inhibits enzymes in the biosynthetic pathway of bacterial peptidoglycan, which is an integral structural component of the bacterial cell wall. Clavulanic acid is a beta-lactam structurally related to penicillins. It inactivates some beta-lactamase enzymes thereby preventing inactivation of amoxicillin. Clavulanic acid alone does not exert a clinically useful antibacterial effect.
• Dosage and administration :
  Neonates and infants aged < 12 weeks (3 months): the recommended dose of Erox CV 30 mg/kg/day divided 12hrly, based on the amoxicillin component.Patients aged 12 weeks (3 months) and older dose is 45 mg/kg/day divided 12hrlyReconstitute powder for oral suspension with purified water.
• Contraindications :
  Hypersensitivity to the active substance(s) or to any of the excipients.Contraindicated in patients with a history of allergic reactions to any penicillin. It is also contraindicated in patients with a previous history of cholestatic jaundice/hepatic dysfunction
• Precautions and warnings :
  periodic assessment of organ system functions, including renal, hepatic, and hematopoietic function, is advisable during prolonged therapy. The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.
• Use in pregnancy, lactation & pediatrics :
  There are no adequate and well-controlled studies in human pregnancy and lactation. This product should only be used in pregnancy if considered essential by the physician.
• Drug interactions :
  Concomitant use of probenecid may result in increased and prolonged blood levels of amoxicillin.
• Adverse reactions :
  The most commonly reported adverse drug reactions (ADRs) are diarrhoea, nausea and vomiting.
• Therapy Area :
  Anti-Bacterials