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S- Celepra (Escitalopram oxalate)

  • Each film coated tablet contains escitalopram oxalate 5mg, 10mg, 20mg.
  • For treatment of major depressive disorder & panic disorders with or without agoraphobia.
  • The mechanism of antidepressant action of escitalopram, the S-enantiomer of racemic citalopram, is linked to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).
  • S- Celepra in MDD for adults and adolescents should generally be administered 10 mg once daily, morning or evening with or without food, Maximum 20 mg once daily.
  • Contraindicated in patients known hypersensitivity to escitalopram or citalopram or any of the inactive ingredients, Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with s-celepra or within 14 days of stopping treatment.
  • Suicide Risk: Monitor for clinical worsening, Serotonin syndrome has been reported with SSRIs and SNRIs. To be prescribed in caution in patients with history of Seizure.
  • Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers: Caution should be exercised when administered to a nursing woman. Pediatric Use: Safety and effectiveness has not been established in pediatric MDD patients less than 12 years of age.
  • Concomitant use with SSRIs, SNRIs or Tryptophan is not recommended, Use caution when concomitant use with drugs that affect Hemostasis (NSAIDs, Aspirin, Warfarin)
  • Most commonly observed adverse reactions are: insomnia, ejaculation disorder, nausea, increased sweating, fatigue and somnolence, decreased libido, and anorgasmia.
  • Anti-Depressants