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Erophylline AC Tablets (Acebrophylline + Acetylcystiene)

  • Acebrophylline 100mg + Acetylcysteine 600mg
  • For the treatment of adult patients with chronic obstructive pulmonary disease (COPD) and bronchial asthma.
  • Acebrophylline inhibits intracellular phosphodiesterase and facilitates bronchial muscles relaxation. Acebrophylline selectively inhibits phosphatidylcholine and phospholipase A, TNF-alpha and leukotrienes. Inhibition of such pro-inflammatory mediators can significantly reduce the airway inflammation and obstruction in chronic stages. Acetylcysteine reduces the viscosity of bronchial mucus.
  • Usual dose : One tablet twice a day
  • Hypersensitivity to acetylcysteine, acebrophylline or to any of the excipients
  • acebrophylline: Careful monitoring is recommended for patients with congestive heart failure, chronic alcoholism, hepatic dysfunction, or viral infections. Caution should be exercised in patients with cardiac arrhythmias, other cardiovascular diseases, hyperthyroidism or hypertension, gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution. Acetylcysteine-Caution should be exercised in patients with increased risk of hypersensitivity reactions, including Urticaria and Upper gastrointestinal Hemorrhage.
  • Not recommended for use in pregnancy, lactation. and children.
  • The following drugs reduce clearance and a reduced dosage may therefore be necessary to avoid side-effects: allopurinol, cimetidine, diltiazem, and erythromycin.
  • Abdominal discomfort, stomach/abdominal distension, vomiting, abdominal pain, diarrhea and constipation
  • Anti-Asthmatics_Bronchodilators