Cholecalciferol (vitamin D3) is a natural precursor of the calcium-regulating hormone calcitriol. Cholecalciferol is produced in the skin by photochemical conversion of 7-dehydrocholesterol to previtamin D3 by ultraviolet light. It stimulates intestinal calcium absorption, incorporation of calcium into the osteoid, and release of calcium from bone tissue.
1-2 drops or as directed by physician.
In patients with a hypersensitivity to any component of this product, hypercalcaemia, hypercalciuria. malabsorption syndrome, hypervitaminosis D,nephrolithiasis.
product should be prescribed with caution to patients suffering from
sarcoidosis, impairment of renal function.
There are no well-established study in pregnant women. Cholecalciferol and its metabolites are excreted in breast milk. Hence, avoid during lactation. Safety and efficacy have not been established in children. Hence not indicated.
Cholestyramine may impair intestinal absorption of vitamin D, Thiazides are known to induce hypercalcaemia, hence careful co-administration with Vitamin D Steroids, some anti-seizure drugs, Statins interfere with Vitamin D metabolism.