Micronac Eye Drops ( Nepafenac)

• Composition :
  Nepafenac ophthalmic suspension 0.1%
• Indications :
  For the treatment of pain and inflammation associated with cataract surgery
• Pharmacodynamics :
  After topical ocular dosing, nepafenac penetrates the cornea and is converted by ocular tissue hydrolases to amfenac, a nonsteroidal anti-inflammatory drug. Amfenac is thought to inhibit the action of prostaglandin H synthase (cyclooxygenase), an enzyme required for prostaglandin production.
• Dosage and administration :
  One drop should be applied to the affected eye three-times-daily beginning 1 day prior to cataract surgery, continued on the day of surgery and through the first 2 weeks of the postoperative period
• Contraindications :
  Hypersensitivity to any of the ingredients in the formula or to other NSAIDS
• Precautions and warnings :
  Increased bleeding time due to interference with thrombocyte aggregation. Delayed healing Corneal effects including keratitis.
• Use in pregnancy, lactation & pediatrics :
  There are no adequate and well-controlled studies in pregnant women, nursing woman and in pediatric patients below the age of 10 years have not been established.
• Drug interactions :
  drug-drug interactions involving CYP mediated metabolism of concomitantly administered drugs are unlikely. Drug-drug interactions mediated by protein binding are also unlikely.
• Adverse reactions :
  Capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, and sticky sensation
• Therapy Area :
  Opthalmologicals