Hicet L Tablets (Levocetirizine)

• Composition :
  Each film-coated tablet contains Levocetirizine 5 mg.
• Indications :
  For treatment of allergic rhinitis & chronic urticaria.
• Pharmacodynamics :
  Levocetirizine, the active enantiomer of cetirizine, is an anti-histamine; its principal effects are mediated via selective inhibition of H1 receptors.
• Dosage and administration :
  Adults and adolescents 12 years and above: The daily recommended dose is 5 mg (1 tablet) once daily in the evening.
• Contraindications :
  Patients with a known hypersensitivity to levocetirizine or any of the ingredients of HICET-L or to cetirizine. Patients with end-stage renal impairment at less than 10 mL/min creatinine clearance or patients undergoing hemodialysis. Children 6 to 11 years of age with renal impairment.
• Precautions and warnings :
  Concurrent use of levocetirizine with alcohol or other central nervous system depressants should be avoided because additional reductions in alertness and additional impairment of central nervous system performance may occur.
• Use in pregnancy, lactation & pediatrics :
  There are no adequate and well-controlled studies in human pregnancy and lactation. The safety and effectiveness in pediatric patients under 6 years of age have not been established.
• Drug interactions :
  Ritonavir increased the plasma concentration of cetirizine. Small decrease in the clearance of cetirizine caused by a 400 mg dose of theophylline.
• Adverse reactions :
  The most common adverse reactions were somnolence, nasopharyngitis, fatigue, dry mouth, and pharyngitis.
• Therapy Area :
  Anti-Allergics