Hicet DC Tablets (Cetirizine + Phenylephrine Hydrochloride)

• Composition :
  Each tablet contains: Cetirizine 10 mg + Phenylephrine 10mg
• Indications :
  Indicated for the symptomatic treatment of allergic rhinitis, fever and nasal congestion
• Pharmacodynamics :
  Cetirizine is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H1 receptors. Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system.
• Dosage and administration :
  One tablet daily
• Contraindications :
  Contraindicated in patients with hypersensitivity to cetirizine or its parent compound hydroxyzine.
• Precautions and warnings :
  Concurrent use with alcohol or other CNS depressants may cause additional reductions in alertness and impairment of performance. Caution in epileptic patients and patients at risk of convulsions is recommended.
• Use in pregnancy, lactation & pediatrics :
  There are no adequate and well-controlled studies in human pregnancy, lactation.
• Drug interactions :
  There was a small decrease in the clearance of cetirizine caused by a 400-mg dose of theophylline; it is possible that larger theophylline doses could have a greater effect.
• Adverse reactions :
  Fatigue, dry mouth and somnolence
• Therapy Area :
  Anti-Allergics