Sodium Feredetate is a vital component of hemoglobin. Sodium Feredetate is a component of myoglobin, a pigment which stores oxygen in muscle.
For oral administration: In Children: Treatment of iron-deficiency anaemia in all paediatric age groups is 3-6 mg/kg (max 200 mg) of elemental iron daily given in 2-3 divided doses. In Adults: 5ml increasing gradually to 10ml 2-3 times daily. In Elderly (over 65 years): As for adults.
The use of this product is contraindicated in patients with hypersensitivity to any of the ingredients of this products. Iron preparations are contraindicated in patients with haemochromatosis, haemosiderosis and in patients with in patients receiving repeated blood transfusions or parenteral iron therapy.
Caution should be taken in patients with haemolytic anaemia, iron-storage or iron-absorption diseases or existing gastrointestinal diseases. Iron preparations colour the faeces black, which may interfere with tests used for detection of occult blood in the stools. Prolonged or excessive use in children may lead to toxic accumulation.
Administration of drugs during the first trimester of pregnancy requires careful assessment of potential risks versus benefits to be gained. No adverse events associated with sodium feredetate administration during pregnancy and lactation have been reported.
Avoid concomitant administration of oral iron with dimercaprol (formation of toxic compounds). Iron reduces the absorption of penicillamine, mycophenolate, fluoroquinolones, levodopa, carbidopa, thyroxine and bisphosphonates. Administration of oral iron may reduce the hypotensive effect of methyldopa. Iron and tetracyclines reduce the absorption of each other.
The most common adverse effects are hypersensitivity, mild diarrhoea, nausea.
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