Dolowin TC Tablets (Aceclofenac + Thiocolchicoside)

• Composition :
  100 mg + Thiocolchicoside 4mg/8mg tablets.
• Indications :
  For the treatment of acute inflammation conditions associated with spasm in adults only.
• Pharmacodynamics :
  Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties. Thiocolchicoside has an affinity for the inhibitory glycine and gamma aminobutyric acid (GABA A) receptors i.e., have glycomimetic and GABA mimetic activity, therefore shows muscle relaxant action
• Dosage and administration :
  One tablet twice daily after food orally.
• Contraindications :
  Contraindicated in patients with a history of or active, recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding) and in patients with known sensitivity to this drug or other any other ingredients.
• Precautions and warnings :
  Cautiously administer to patients with GI disease, ulcerative colitis, Crohn`s disease, hematological abnormalities, hepatic porphyria; history of bronchial asthma, history of heart failure or hypertension; mild renal hepatic or cardiac impairment.
• Use in pregnancy, lactation & pediatrics :
  Not recommended in pregnant woman as there is no information during pregnancy. The drug is not recommended in lactating women. Not recommended in children under 18 years of age.
• Drug interactions :
  Avoid concomitant use of two or more NSAIDs (including aspirin) as this may increase the risk of adverse effects. NSAIDs may exacerbate cardiac failure, reduce the glomerular filtration rate (GFR) and increase plasma glycoside levels.
• Adverse reactions :
  The most common side-effects are nausea, Vomiting, Stomach pain, indigestion, heartburn, loss of appetite, diarrhoea,somnolence, fatigue, dry mouth, and pharyngitis.
• Therapy Area :
  Anti-Inflammatories