Nilac Gel (Clindamycin phosphate + Nicotinamide with Aloe )

• Composition :
  Clindamycin phosphate 1% w/w + Nicotinamide 4% w/w with Aloe
• Indications :
  Topical treatment for acne
• Pharmacodynamics :
  Topical clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes), an anaerobe found in sebaceous glands and follicles. Nicotinamide has anti-inflammatory and sebostatic role in acne.
• Dosage and administration :
  Apply a thin layer onto affected area twice daily
• Contraindications :
  Hypersensitivity to the active ingredients or any other excipients of the formulation. a history of regional enteritis or ulcerative colitis, or a history of antibiotic associated colitis.
• Precautions and warnings :
  Renal and hepatic diseases; GI disease; elderly, females, neonates, atopic patients. Regular monitoring of blood counts, liver and kidney functions. Caution is exercised in atopic individuals.
• Use in pregnancy, lactation & pediatrics :
  There are no adequate and well-controlled studies in this population.
• Drug interactions :
  Clindamycin may enhance the action of other neuromuscular blocking agents, Cholinergics and Erythromycin: Antagonism, hence should be used with caution. There is risk of myopathy/rhabdomyolysis on adminictration with statins.
• Adverse reactions :
  The most common adverse reactions are skin dryness, pruritus, erythema, irritation, flushing.
• Therapy Area :
  Dermatologicals and Cosmetologicals