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Hypotab Chewable Tablets (Dextrose)

  • Each chewable tablet contains Dextrose 4gm.
  • Indicated in hypoglycaemia.
  • Glucose supplies most of the energy to all tissues by generating energy molecules ATP and NADH during a series of metabolism reactions called glycolysis. Glycolysis can be divided into two main phases where the preparatory phase is initiated by the phosphorylation of glucose by hexokinase to form glucose 6-phosphate. The addition of the high-energy phosphate group activates glucose for the subsequent breakdown in later steps of glycolysis and is the rate-limiting step. Products end up as substrates for following reactions, to ultimately convert C6 glucose molecule into two C3 sugar molecules. These products enter the energy-releasing phase where the total of 4ATP and 2NADH molecules is generated per one glucose molecule. The total aerobic metabolism of glucose can produce up to 36 ATP molecules. These energy-producing reactions of glucose are limited to D-glucose as L-glucose cannot be phosphorylated by hexokinase.
  • Make sure not to swallow this medicine (dextrose chewable tablets). It may be repeated in 10 minutes if blood sugar is still low. Chew well before swallowing.
  • Hypersensitivity to the active substances or to any of the excipients.
  • Possible hyperosmolar syndrome may result in patients with chronic uremia and those with known carbohydrate intolerance. Moderate hypoglycaemic symptoms without loss of consciousness or neurological manifestations should be corrected by the immediate intake of sugar. An adjustment to the dosage and/or changes to meal patterns should be ensured. Lactic acidosis is a rare, but serious (high mortality in the absence of prompt treatment), metabolic complication that can occur due to metformin accumulation.
  • Pregnancy Category C. It is not known whether this drug is excreted in human milk.
  • No drug drug interactions reported.
  • The most common adverse reactions are upset stomach, loose stools.
  • Anti-Hypoglycaemic agents