New DoloCold Tablets (Paracetamol + Caffeine + Phenylephrine + Chlorpheniramine Maleate ).

• Composition :
  Paracetamol 325 mg + Phenylephrine hydrochloride 10 mg + Chlorpheniramine maleate 2 mg + Caffeine 30 mg.
• Indications :
  Indicated for the treatment of fever associated with cold, nasal congestion in adults.
• Pharmacodynamics :
  Paracetamol is an analgesic and antipyretic drug for management of fever and mild-to-moderate pain. Phenylephrine is sympathomimetic vasoconstrictor that has been used as a decongestant. Chlorpheniramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. Caffeine enhances the analgesic activity of Paracetamol and serves to reduce incidence of sedation due to Chlorpheniramine maleate.
• Dosage and administration :
  The usual recommended dose is 1-2 tablets three time a day.
• Contraindications :
  Hypersensitivity to any of the ingredients/components of the product.
• Precautions and warnings :
  NEW DOLO COLD contains Paracetamol and therefore should not be used in conjunction with other Paracetamol containing products. Dolocold should be used with caution in patients with renal or hepatic dysfunction, diabetes mellitus, hyperthyroidism, cardiovascular problems, epilepsy and closed angle glaucoma.
• Use in pregnancy, lactation & pediatrics :
  Not recommended for use in pregnancy and lactation.
• Drug interactions :
  Drug interactions may occur on concomitant administration of Dolocold with monoamine oxidase inhibitors, tricyclic antidepressants, beta-adrenergic agents, methyldopa, reserpine and veratrum alkaloids.
• Adverse reactions :
  Generally well tolerated and adverse events are rare. Hypersensitive individuals may display ephedrine-like reactions, such as tachycardia, palpitations, headache, dizziness and nausea.
• Therapy Area :
  Cough & Cold Preparations