for treatment of patients with serious cerebral injuries of vascular traumatic nature with or without loss of consciousness and for treatment of degenerating damages and chronic cerebral vascular injuries in senile dementia.
Citicoline is a pyrimidine 5’-nucleotide, which serves as an essential precursor in the synthesis of lecithin (phosphatidylcholine) and other phospholipids associated with cell proliferation. Citicoline appears useful for improving both the structural integrity and functionality of the neuronal membrane that may assist in membrane repair.
Dosage should be individualized. The usually recommended dose of tablet is 500 – 1,000 mg daily. No dosage adjustment is required for the elderly population and the usual recommended adult dose can be administered.
Hypersensitivity to Citicoline or any of the ingredients in the formulation. Citicoline is contraindicated in patients with hypertonia of the parasympathetic nervous system.
In case of persistent intracranial hemorrhage, it is recommended not to exceed the dose of 1,000 mg of Citicoline daily.
There are no adequate and well-controlled studies of citicoline during pregnancy. Citicoline should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised during breastfeeding because it is not known whether citicoline is excreted in breast milk.
Citicoline may enhance the effects of levodopa, carbidopa and entacapone, caution should be exercised and should not be administered in conjunction with medications containing centrophenoxine.
Most commonly adverse reactions with Citicoline tablet are excitation, convulsions, anorexia, transient diplopia, transient blood pressure changes, malaise, shock, distressed feeling of the chest, and dyspnea.
Doctors
Nurses
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