Nicerbium Tablets (Nicergoline 30 mg ).

• Composition :
  Each tablet contains 30mg of Nicergoline.
• Indications :
  Indicated in the treatment of acute & chronic peripheral and cerebral vascular metabolic disorders, Raynaud's syndrome and all syndromes due to altered peripheral flow.
• Pharmacodynamics :
  Nicergoline has a broad spectrum of action: (i) as an alpha adrenoceptor antagonist, it induces vasodilation and increases arterial blood flow; (ii) it enhances cholinergic and catecholaminergic neurotransmitter function; (iii) it inhibits platelet aggregation; (iv) it promotes metabolic activity, resulting in increased utilization of oxygen and glucose; and (v) it has neurotrophic and antioxidant properties
• Dosage and administration :
  30 mg/day in Cerebrovascular insufficiency. 30 mg twice per day, for Peripheral Vasodilatation.
• Contraindications :
  Contraindicated in hypersensitivity to nicergoline or any of the drug constituents
• Precautions and warnings :
  Nicergoline, as other adrenergic blocking agents, may significantly reduce blood pressure (arterial hypotension) in some patients.
• Use in pregnancy, lactation & pediatrics :
  Do not administer this product if pregnant, if pregnancy is suspected or during breast-feeding. There are no adequate and well-controlled studies in this population hence should not be used.
• Drug interactions :
  Nicergoline is known to potentiate the cardiodepressant effects of propranolol.
• Adverse reactions :
  Drowsiness, tiredness, constipation, pyrosis, vomiting, diarrhea, facial flushing, sexual impotence and libido reduction, uric acid increment
• Therapy Area :
  Cerebral Activators_Nootropics