Neurovin Tablets (Vinpocetine ).

• Composition :
  Each Neurovin tablet contains 5 mg of Vinpocetine.
• Indications :
  For the treatment of Psychic or neurological symptoms of cerebral circulatory disturbances of various origin e.g., impaired memory, locomotor disorder
• Pharmacodynamics :
  Vinpocetine has calcium - channel blocking activity, as well as voltage-gated sodium channel blocking activity. It inhibits the acetylcholine release evoked by excitatory amino acids and to protect neurons against excitotoxicity. In addition, inhibits a cyclic GMP phosphodiesterase. This inhibition enhances cyclic GMP levels in the vascular smooth muscle, leading to reduced resistance of cerebral vessels and increase of cerebral flow.
• Dosage and administration :
  One tablet 3 times daily.
• Contraindications :
  It is contraindicated in cases of known hypersensitivity to vinca alkaloids such as vinblastine and vincristine.
• Precautions and warnings :
  Those with hypotension or orthostatic hypotension should be cautioned that prolonged use of vinpocetine may lead to slight reductions in systolic and diastolic blood pressure.
• Use in pregnancy, lactation & pediatrics :
  Use during pregnancy may harm the baby or result in miscarriage. Safety and efficacy not established in nursing mothers and pediatric patient.
• Drug interactions :
  Slight changes in prothrombin time have been noted in those adding Vinpocetine to warfarin.
• Adverse reactions :
  Most common adverse effects are GI upset, nausea, anxiety, dizziness, sleep disturbances or headache.
• Therapy Area :
  Cerebral Activators_Nootropics