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Haloderm S ointment (Halobetasol + Salicyclic acid)

  • Halobetasol (0.5%) + Salicylic acid (3%) Ointment.
  • For the treatment of plaque psoriasis.
  • Halobetasol propionate possesses anti-inflammatory, anti-pruritic and vasoconstrictive properties. The drug induces phospholipase A2 inhibitory proteins such as lipocortins. The protein inhibits the biosynthesis of pro-inflammatory mediators such as leukotrienes and prostaglandins by inhibiting arachidonic acid, a precursor of pro-inflammatory mediators.Salicylic acid has keratolytic action and better penetration of Halobetasol.
  • Apply a thin layer of Halobetasol Propionate to the affected skin twice daily for up to two weeks. Rub in gently. Discontinue when symptoms are reduced.
  • Contraindicated in individuals who have shown hypersensitivity to any of its active excipients.
  • Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression may occur, Systemic absorption may require evaluation for HPA axis suppression
  • Pregnancy Category C. There are no adequate and well-controlled studies of acyclovir cream in pregnant women. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Halobetasol Propionate is excreted in breast milk. caution should be exercised when drug is administered to a nursing woman. Safety and effectiveness of halobetasol in pediatric patients have not been established and use in pediatric patients under 12 is not recommended
  • Systemic effects of topical corticosteroids may also include Cushing’s syndrome, hyperglycemia, and glucosuria. Use of potent corticosteroids on large areas, for prolonged durations, under occlusive dressings, or on an altered skin barrier may increase systemic exposure
  • The most commonly reported adverse reactions are telangiectasia, application site atrophy, and headache
  • Dermatologicals and Cosmetologicals