Zolipid Tablet (Zolpidem )

• Composition :
  Each Tablet contains 10 mg of zolpidem tartrate.
• Indications :
  Treatment of insomnia.
• Pharmacodynamics :
  Subunit modulation of the GABAA receptor chloride channel macromolecular complex is hypothesized to be responsible for sedative, anticonvulsant, anxiolytic, and myorelaxant drug properties.
• Dosage and administration :
  10 mg once daily immediately before bedtime
• Contraindications :
  Known hypersensitivity to zolpidem tartrate or to any of the inactive ingredients in the formulation.
• Precautions and warnings :
  Severe anaphylactic/ anaphylactoid reactions, abnormal thinking, behavioral changes and complex behaviors. Symptoms may occur with rapid dose reduction or discontinuation, worsening of depression or, suicidal thinking may occur. Re-evaluate if insomnia persists after 7 to 10 days of use. Impairment of alertness and motor coordination. Use with caution and monitor closely in patients with hepatic impairment.
• Use in pregnancy, lactation & pediatrics :
  Pregnancy: Crosses the placenta. No studies in pregnant women. Nursing mothers: Infant exposure via breast milk. Pediatric use: Safety and effectiveness not established.
• Drug interactions :
  Enhanced CNS-depressant effects with combination use, decreased alertness with imipramine, combination use with rifampicin decreases zolpidem effects. Ketoconazole increases exposure to and effect of zolpidem.
• Adverse reactions :
  Drowsiness, dizziness and diarrhea.
• Therapy Area :
  Hypnotics