Each tablet contains Progesterone SR 200/300mg (Natural Micronized).
Indicated in the treatment of secondary amenorrhea and functional uterine bleeding of hormonal imbalance, insufficient secretion of progesterone in women participating in fertilisation programme.
It acts on the endometrium by converting the proliferating phase to the secretory phase.
Prevention of Endometrial Hyperplasia: should be given as a single daily dose at bedtime, 200 mg orally for 12 days sequentially per 28-day cycle, to a postmenopausal woman with a uterus who is receiving daily conjugated estrogens capsule. Treatment of Secondary Amenorrhea: may be given as a single daily dose of 400 mg at bedtime for 10 days.
Fulgest Capsule should not be used in patients with known hypersensitivity to its ingredients. Undiagnosed abnormal genital bleeding, Known, suspected, or history of breast cancer.
An increased risk of pulmonary embolism, deep vein thrombosis (DVT), stroke, and myocardial infarction has been reported with estrogen plus progestin therapy. Should any of these occur or be suspected, estrogen with progestin therapy should be discontinued immediately.
should not be used during pregnancy, should not be used in children.
Ketoconazole is a known inhibitor of cytochrome P450 3A4, hence these data suggest that ketoconazole or other known inhibitors of this enzyme may increase the bioavailability of progesterone.
Doctors
Nurses
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