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Pantotab L capsules (Pantoprazole +Levosulpiride ).

  • Each capsule contains Pantoprazole 40 mg and Levosulpiride 75 mg SR.
  • For short term treatment of GERD in adult patients who do not respond to PPI alone.
  • Pantoprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+ /K+ -ATPase in the gastric parietal cell. Levosulpiride is a prokinetic agent with dual mechanism of action. It blocks the enteric dopamine (D2) receptors (both neuronal & muscular) and also acts as an agonist at serotonin (5-HT4) receptor.
  • One capsule once daily before meals.
  • Hypersensitivity to any of the ingredients/components of the product.
  • Atrophic gastritis has been noted with long-term therapy. Bone Fracture: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine.
  • There are no adequate and well-controlled studies in human pregnancy, lactation and infants. This product should only be used in pregnancy if considered essential by the physician. The safety and effectiveness for pediatric use other than Erosive Esophagitis have not been established.
  • Concomitant warfarin use may require monitoring.
  • The most common side-effects are headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia.
  • Anti-ulcerants_Gastroenterologicals