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Spasmopriv Capsules (Fenoverine).

  • Fenoverine 100 mg/ 200 mg Capsules.
  • For the treatment of smooth muscle spasm of gastro intestinal tract & Irritable Bowel Syndrome (IBS).
  • Fenoverine exerts its action by inhibiting calcium ion (Ca+2) channels. This will inhibit the rapid influx of (Ca+2) through the voltage dependent channels and also inhibits the release of Ca+2 from the storage site. Thus Fenoverine effectively synchronizes the strong asynchronous spasmodic contractions, relieving the spasm and the associated symptoms.
  • 100 mg t.i.d or 200 mg bid for not > 6 wk. Elderly: Max: 100 mg t.i.d.
  • Fenoverine is contraindicated in hypersensitivity, chronic liver disease, history of hyperthermia during or after anaesthesia or after physical effort, renal insufficiency and mitochondrial myopathy.
  • Caution should be exercised in patients with history of renal or hepatic impairment, muscle pain, chest pain, during pregnancy and breastfeeding.
  • There are no adequate and well-controlled studies, safety & efficacy of fenoverine in these populations have not been established.
  • Most common adverse reactions are myalgia, gastric upset, flushing, photophobia, dry mouth and constipation.
  • Anti-Spasmodics