Olan Tablets (Olanzapine).

• Composition :
  Each tablet contains Olanzapine 2.5 mg/5 mg/10 mg.
• Indications :
  For treatment of schizophrenia in adults.
• Pharmacodynamics :
  Olanzapine efficacy in Schizophrenia is mediated through a combination of dopamine and serotonin type 2 (5HT2) antagonism.
• Dosage and administration :
  Oral: Start at 5-10 mg once daily; Target: 10 mg/day within several days.
• Contraindications :
  Contraindicated in patients with known hypersensitivity to Olanzapine, in combination with fluoxetine
• Precautions and warnings :
  Elderly Patients with dementia-related psychosis; Neuroleptic Malignant Syndrome: Patients taking olanzapine should be monitored for symptoms of hyperglycemia.
• Use in pregnancy, lactation & pediatrics :
  Pregnancy Category C. should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers: Breast feeding is not recommended. Pediatric Use: Safety and effectiveness in children and adolescent patients have not been established.
• Drug interactions :
  Diazepam: May potentiate orthostatic hypotension; Alcohol: May potentiate orthostatic hypotension; Carbamazepine: Increased clearance of olanzapine.
• Adverse reactions :
  Most common adverse reactions postural hypotension, constipation, weight gain, dizziness, personality disorder and akathisia.
• Therapy Area :
  Anti-Psychotics